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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72241f4abd108bfc7287c340ab7b5b232f3b68983eb7ce552af62bb244a1dc6' 
  AND token = '12PlTPoXoG64DsakXkc0Hcr5xN2h2et3VuczrW+T5vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}