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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8337f5d2f7b0c194e2db93d9901d68d79d64ff826744fe43111e183dd957d5c' 
  AND token = 'hAJ+gFN5ZaaSybqMCeVrK7m6S+83EATnvObxbzaNYdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}