SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa458bc3c947f65853e8ed3ce1cffe2c429c1fea73b96b50ef73dc23afcba1b' 
  AND token = 'U5bil8n9Uq4hW6bgG+bTJn2I2nCiZtAxmPDDhcH26e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}