SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa8e4060dddcb85566cf732a5ebc078e734914f53eadaca35ccdf0bebecbf66' 
  AND token = 'An+V58WZU0ubcI+EPvJOglqbCQJlxTOpeNLmwDVUIV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}