SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '393b26a0470bc134315dae7627c1b8bf2f424609832006f3c9cf163c013d10a7' 
  AND token = 'tPmuxdsEZuC/WC6JfZes3IF+KMIpNsly4Qe/VdAFWl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}