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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d181a4af2ada069ef5348f62c518c73e80e7a877d3e02a5e72d7028d14b6e91' 
  AND token = 'blZaB5EZ6iS5IiiAnucZs/x4+RajeZSKeBpLOfCISAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}