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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd246f46416eed9a2e6d340647bdf08c7675bf0873eb58a57a088e077a2270a4a' 
  AND token = 'xPZA+1F8tX2X1LFUcja1DFru2zkACP97fEstCjkis2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}