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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e0fab9ccff7b8e2b710118aa929068aa17422e2b628e8733dd46bf1507eb06' 
  AND token = 'Hz43I7fbN02wB0/ElnSL5AM8c04CZ4P3kMNCzntKYfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}