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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260f10f930aad2388e85ecd9c938de0b7b1bcf8e6f572faba696c5276a02273a' 
  AND token = 'En2R+hzhpeZ/L1FkuvbBC26ZfjistBy90TmY8rsFni0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}