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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b201fac6a7980ad8e15942cfac5fb751794f5d689ae6a0b1ccdd29e4afd4da' 
  AND token = 'WYaSJf1PRUPr0JAhw9/FsK9ApIWYgdFDIf5Gjq6i7Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}