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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b34c7a39a95cbb9ef4ee351d9c87911fe298fec03076d16595d644ff3412f81' 
  AND token = 'uFcZS2Gfuwj7RVQWcD3k2yYUBTuc5R3c/WRLzPPxpm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}