SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffd4b7ce3e68e29dded471ee78d03cc70b8b8dad4814a6f132c721479ae0bff' 
  AND token = 'wZt5E/sBqq/K8a4UioVVHFhmQq07vRHhjGsQqEDKXZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}