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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1aeb962b97c09257abcc89ed3a4546612fa9767b5ba8e5d311adfce3b71047c' 
  AND token = 'jrxPrIX2vE3SPwLdojCxpuZlhdQ0iCl6DCXNPesP+gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}