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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f427fd421d91e1f9403f6d9026e2e57df7cd079864fd72d8b42357be11a9bc' 
  AND token = 'LPXoqYY0uEepnRuL/usckbo+wNRkgOf/K6maafL1ZhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}