SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2b981da3a97a9271e3dfd09cefdfda4691760c1b8dd3acabdb68ae998ec2bb' 
  AND token = '4ivuxM+ARP9GHey7dXo8i4uF5UtOB0WRScpea448y30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}