SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb9e9e4b53f53b9ec50390d76c283f447bee131c8d4e94074a82f6b2daf80ef' 
  AND token = '+u2UuGZRmlv11tLGYg1LaQfJ23gh2fcq8PmcdeprctM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}