SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70777209a5fcbc6bb499ffba6a75ef52ee912fb010975b6c5da0f461ae8a0c34' 
  AND token = 'Ck+O9vThctvUBdD1JhksWcDR8rOHvvIqXh9FjJLuJS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}