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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cce00eb2668693070c3e5757c0b4149725741911ae5288df6ee2d1cc00638b' 
  AND token = 'YCnKhnC02nuik0c9/585XZs1YzxXb9kCD6WTZf1mtHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}