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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfca8d2ea048e52b2033522a1842cebd2b665e179cd722499333967c09d21a25' 
  AND token = 'RyJM3B0NYmgv0PmcuKncTm5osv9wNpNyOoH1j9+ADJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}