SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6372351db8e433c67f57ef64ee63d4cc1864c0e0d4d7638b115d8ab10219e178' 
  AND token = 'WIDy56RzLnt0AGfpxsjmXu/HASEu4KfUsitE9pmmHOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}