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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd252907f8d628e6cf8166c308495584da5a732626e7711ea0b2c1ef1d49a555' 
  AND token = 'XsXJdMApscGmL5EcPc605jfAT3wrTqcN0MdPcY0DmrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}