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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe9fd278e4fc68c121af21f41edd88840e0815d00ef33d1c821cf9944312f3e' 
  AND token = 'hrRxjEFY/DarurBz2EiJdQFHPpqi5hgHNCZ9u7eYa7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}