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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea406c99defc74c243b3d7920998b740c54f3db37421817cad538a1a73a278ea' 
  AND token = 'p5Pb4y2+FdqBn4w+GqxKThtLgm4mWr3NAtf2bG7GvlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}