SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '524a2205c6d4e4d546d0e75780db01a3d3ffb79ece708abf1fc9e37b0ff15072' 
  AND token = 'n1KAv12wJvBfdug7eX++tXLmlTa4BGLANfbPGY+kLAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}