SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34af36ceeaf95cd6a046eadbe82bf1029581facbd82b721f01c973740a4e8cc1' 
  AND token = 'NWsdIjCw/7xqCS9bzDyTixEp1nMkNBklcp9jw6UGZDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}