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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea29b6720d6cc4ec124c5056f154fec42979e748ac0ae1083a040beb2a23f32' 
  AND token = 'wpx9DN6MwrlRV3xGAFXC4RrFvAUOkw13p2E4maKuPBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}