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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d3c65eb1092c7ced8da95403248a73ddce44d7098dc70e610c521d6bc81a4a' 
  AND token = 'OEsDtaG6Z5XDSFJBmfHS6l3Aaio8N4iyk1dWcA4JwjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}