SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e601316f69afce3d14207c70973fa3307a13824f60525959fb54a99d02871e89' 
  AND token = 'X5r68xahe8mCt8Zaz7AOsqVGf5MF3RLeEASyqK1Ufro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}