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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e28912bb56f186e3cf82459ccbd9a6d10933d6f59d9be51072aa71a3d38c48' 
  AND token = 'iCVp9ODpYwEZFswzLuL9MbtjOc10S/ToDhEEROc6Q9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}