SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b217118c021e5965c28513dc4a984f1a23be797dd43b32c3bfeed1cd7113802f' 
  AND token = 'KwrR29uj+zpN49oTbgiXR9x7B3dPmWqPFo0R+HNyPhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}