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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849a8bda0bf93564390aeced58abc6a92aaf65df101f408b70ddcd991408b629' 
  AND token = 'u5+1A7oXu+ucM3pFLmXKzQb/nljKTeaTLtoZ2SYEexE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}