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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b525ea5ab1d0df8a6078b1a8919f707437eb59e13853fc71703c223a50526a6' 
  AND token = 'pZHtMehnsfxNzRtys9M5DAypdeXTXTPKiqo0QbcSD5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}