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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e250ebfb924b6e3aaf63be0d592bff37885c88c93561d1a0ef39a780f17cfd21' 
  AND token = '6mlCcpqXQ5oeB99/M+EAfwGqnCcl4TZCtgq6cnYdwc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}