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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e91bf5aff206a95c906f6c410319be89e7432327a89b63fc52f2df647fa83c4' 
  AND token = 'gL0ya3T+Ih5xRD+HeUEYYmM832iczXaAn8mmt79Qg2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}