SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13e4b96b534897a0df7112796fcd40df325c1bcd890e0e665af82bbee1386ac0' 
  AND token = 'NdI+3wMMIp1U8NjQqYJy02g7FgmVkaR26KgUKLoerTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}