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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8ccc5aec03bfc98b3aea8f7c9c0b657d7a0152180fc37388b9821e31bb7bd3' 
  AND token = 'DT/zAUwVbTG/lj2PKL7pN9gZoovMWJOrLZEgBXtNGdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}