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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1950fc8a3c88a375add17cd276b71a31826810b22d35f44a0170b799ba96e7' 
  AND token = 'qNkaQIZ1iF8whoPx37beN5DYIGFMLBfxwp3lgsl1mbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}