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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa96a5cf93e481be3ffffa727636145e234169e793f8d91e5df3f19d8d189165' 
  AND token = 'nlvO4jkRhLe55M+Q/MbDHayyWJURNdL9SAlYhzaW0bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}