SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ab91fcf8a222a270538f5ec4611c1795c13519ab8a315ee0c71139b69868f8' 
  AND token = '6yHmzq1ImNh/yhpYAiR76JpXPoW7iAYPRCcwly4sTa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}