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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe7d0e4f2c26d7ea1373411dbaa26f42123c4870d699cdfa6f935e7c10674a66' 
  AND token = 'RuRDYQlmHHyrr2qJnHlAb8j2LAVJN8Qjm+XlMoDY3gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}