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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1b8ac90b99b87ef00b9197602011d2060fb9b0823f0b40097ebe914574e458' 
  AND token = 'vHD/lwxQ4Acy2XE9i2+uj+J9yVQSm4cRbnXp+CKvTjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}