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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e388b16cfb6c1510af3eb74a08383210380dbbc43fd25b47d6f0dd305a5f8805' 
  AND token = 'dp+Wf0GuYtaYO41dXzHV6HpmmQoS/V/EusnMEBlbO+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}