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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d87cd4f062618938f0db90aee6ce90170cc777b149b035334ac111c1690b67c' 
  AND token = 'B84i4DlCT2blWmmn2kS5RVYXRhyveYM+R4+5C59M6bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}