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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8677ed4f7ec699003e08ea3ba6bd379afad70d162b93432954e71d141a1971e' 
  AND token = '1EI9fplBjXuDyrX5su3CJUrM4Is734uOA+LpNccQm+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}