SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f149c55bf7c9d088f1adbff440e98568685aa586126af925605cce670542edb8' 
  AND token = 'ApcqCmMy2l8mFurAR+2qg/hHJ4Uy9OMsb2Qbty9ibsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}