SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df60e114cc72046e25e58e0ff57a0a4626ccbdff68dee6a01eff3ab2715e187' 
  AND token = '/ehUhNXOkylH/dmIq8KozHjlPMvqJsOrbXUng1e5UB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}