SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2ba44b4b809c0e0134a251057fb4034b6dfe7a46d4ebea72b055c67c827f03' 
  AND token = 'HCUqNE4xKde3ritEH1806XB85XRgackked59qHxu77c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}