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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0043619c19a299070914b14f71c7c23aa058c52a60089921a94a59759ccb94ea' 
  AND token = '+SJsu5+k86RU22Bn3NUwL5bxOYZaULGIt6McoRlbC3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}