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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27b114c3830ce12e1e2ce6f9a7293aea54979ac7fa71693f59f0924e4de02d2' 
  AND token = 'BbsM9+NFT5uvALhpCWKdXDIuIUvjKgvCDEyCcX4wT+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}