SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d1a2d4bc47d6374b785fb09dfcc106ae5d4ed0157dd032f5e774f2297420a7' 
  AND token = 'Lo9hAK5axlPWDWh1OoJUzz7xdd823IsI66vodXcVI9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}